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英文 English
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Researchers find 4 potential COVID treatments through AI (2021/02/23)
Using the power of artificial intelligence, Taiwan researchers have found four drugs that may be able to inhibit the COVID virus. One promising drug is JMY206, an anti-inflammatory therapy that was dozens of times more effective against COVID-19 than Remdesivir. Partial results of this study were published in ACS Nano, a journal by the American Chemical Society.
The research team at National Yang Ming Chiao Tung University used AI and SARS datasets to identify key proteases in the COVID virus and see whether different FDA-approved drugs could inhibit them. Three other drugs that showed promise against the COVID virus were hepatitis C treatments Boceprevir and Telaprevir, as well as Nelfinavir, which treats HIV.
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中文 Chinese
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陽明交大以AI找出C肝老藥物 抑制新冠病毒
陽明交大團隊透過AI技術，找出4款舊藥可以抑制武漢肺炎病毒活性，其中一款抗發炎藥，經動物實驗證實，效力比起瑞德西韋強數十倍，為治療武漢肺炎帶來一線曙光，部分成果已發表在《美國化學學會月刊：奈米領域(ACS Nano)》。
研究團隊從FDA藥庫，還有SARS以來累積的資料，利用AI比對出關鍵蛋白質，經過多次篩選後，找出抑制武肺病毒活性的潛力藥物，包括抗C型肝炎病毒藥物巴色匹韋(Boceprevir)、特拉匹韋(Telaprevir)，抗愛滋病藥物奈非那韋(Nelfinavir)，以及效力比瑞德西韋強數十倍的抗發炎舊藥(JMY206)。
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